Evolutionary Genetics # MCQs Practice set

Q.1 Who is considered the father of evolutionary theory?

Gregor Mendel
Charles Darwin
Alfred Wallace
Thomas Hunt Morgan
Explanation - Darwin proposed natural selection as the main driving force of evolution, making him the father of evolutionary theory.
Correct answer is: Charles Darwin

Q.2 Which process introduces new genetic variation into a population?

Mutation
Selection
Drift
Migration
Explanation - Mutations are random changes in DNA sequences and are the ultimate source of new genetic variation.
Correct answer is: Mutation

Q.3 What does gene flow refer to?

Transfer of genes between populations
Random loss of alleles
Formation of new species
Mutation within DNA
Explanation - Gene flow occurs when individuals migrate and reproduce in a new population, transferring alleles.
Correct answer is: Transfer of genes between populations

Q.4 Genetic drift is most significant in:

Large populations
Small populations
Stable populations
Populations with high mutation rates
Explanation - Genetic drift is random fluctuation in allele frequencies, which has stronger effects in small populations.
Correct answer is: Small populations

Q.5 The modern synthesis combines Darwin’s theory of natural selection with:

Mendelian genetics
Lamarck’s inheritance
Cell theory
Chromosomal theory
Explanation - The modern synthesis unified Darwin’s ideas with Mendel’s genetic principles, explaining evolution in genetic terms.
Correct answer is: Mendelian genetics

Q.6 Which term describes the ability of an organism to survive and reproduce?

Adaptation
Fitness
Variation
Speciation
Explanation - In evolutionary genetics, fitness refers to reproductive success relative to others in the population.
Correct answer is: Fitness

Q.7 The Hardy-Weinberg equilibrium assumes all except:

Random mating
No mutation
No natural selection
Rapid environmental change
Explanation - Hardy-Weinberg assumes no mutation, migration, selection, and random mating in a large population. Environmental change is not part of the model.
Correct answer is: Rapid environmental change

Q.8 Which evolutionary force reduces genetic differences between populations?

Natural selection
Mutation
Genetic drift
Gene flow
Explanation - Gene flow homogenizes populations by introducing alleles from one group into another.
Correct answer is: Gene flow

Q.9 Balancing selection maintains:

Neutral mutations
Genetic diversity
Population size
Mutation rate
Explanation - Balancing selection maintains multiple alleles in a population, preserving diversity.
Correct answer is: Genetic diversity

Q.10 Which of the following is an example of a prezygotic isolation mechanism?

Hybrid sterility
Temporal isolation
Hybrid inviability
Reduced fertility
Explanation - Prezygotic isolation prevents mating or fertilization; temporal isolation occurs when species breed at different times.
Correct answer is: Temporal isolation

Q.11 Founder effect is a type of:

Mutation
Natural selection
Genetic drift
Gene flow
Explanation - Founder effect is genetic drift occurring when a new population is started by a few individuals.
Correct answer is: Genetic drift

Q.12 What is adaptive radiation?

Random genetic drift
Formation of identical traits
Diversification of a lineage into new niches
Gene flow between species
Explanation - Adaptive radiation occurs when species diversify rapidly into different ecological niches.
Correct answer is: Diversification of a lineage into new niches

Q.13 Which type of selection favors intermediate traits?

Directional
Disruptive
Stabilizing
Balancing
Explanation - Stabilizing selection favors average traits and reduces extremes.
Correct answer is: Stabilizing

Q.14 Synonymous mutations are:

Always harmful
Neutral
Beneficial
Lethal
Explanation - Synonymous mutations do not change amino acids, so they usually have no effect on fitness.
Correct answer is: Neutral

Q.15 Molecular clock hypothesis is based on:

Constant mutation rates
Natural selection
Adaptive radiation
Genetic drift
Explanation - The molecular clock assumes mutations occur at a relatively constant rate, useful for dating divergence.
Correct answer is: Constant mutation rates

Q.16 Heterozygote advantage is a form of:

Disruptive selection
Directional selection
Balancing selection
Stabilizing selection
Explanation - Heterozygote advantage maintains diversity by giving heterozygotes higher fitness (e.g., sickle-cell trait).
Correct answer is: Balancing selection

Q.17 Which scientist proposed the neutral theory of molecular evolution?

Charles Darwin
Motoo Kimura
Richard Dawkins
Ernst Mayr
Explanation - Motoo Kimura proposed that most molecular evolution is driven by neutral mutations fixed by drift.
Correct answer is: Motoo Kimura

Q.18 Speciation that occurs due to geographic separation is called:

Allopatric speciation
Sympatric speciation
Parapatric speciation
Peripatric speciation
Explanation - Allopatric speciation occurs when populations are geographically isolated and diverge genetically.
Correct answer is: Allopatric speciation

Q.19 Which evolutionary concept explains the sudden appearance of new species in the fossil record?

Gradualism
Punctuated equilibrium
Adaptive radiation
Neutral theory
Explanation - Punctuated equilibrium suggests species remain stable for long periods, with short bursts of rapid change.
Correct answer is: Punctuated equilibrium

Q.20 The bottleneck effect reduces:

Gene flow
Mutation rate
Genetic variation
Speciation rate
Explanation - Population bottlenecks drastically reduce genetic diversity due to a sharp decline in numbers.
Correct answer is: Genetic variation

Q.21 Horizontal gene transfer is most common in:

Plants
Animals
Bacteria
Fungi
Explanation - Bacteria frequently exchange genetic material via horizontal transfer, accelerating evolution.
Correct answer is: Bacteria

Q.22 Which type of selection results in two distinct phenotypes?

Directional
Stabilizing
Disruptive
Balancing
Explanation - Disruptive selection favors extreme traits, leading to two distinct phenotypic groups.
Correct answer is: Disruptive

Q.23 What is the unit of natural selection?

Population
Species
Individual
Gene
Explanation - Natural selection acts on individuals, but its consequences are seen at the population level.
Correct answer is: Individual

Q.24 Which genetic marker is often used to trace maternal lineage?

Nuclear DNA
Y chromosome
Mitochondrial DNA
Ribosomal RNA
Explanation - Mitochondrial DNA is inherited maternally and is widely used in evolutionary studies.
Correct answer is: Mitochondrial DNA

Q.25 Which evolutionary mechanism explains antibiotic resistance in bacteria?

Mutation and natural selection
Genetic drift
Stabilizing selection
Bottleneck effect
Explanation - Antibiotic resistance arises from mutations that confer survival advantage under drug pressure.
Correct answer is: Mutation and natural selection