Q.1 Which vaccine is the first dose typically given to a newborn within 24 hours of birth?
BCG
Hepatitis B
Polio (OPV)
MMR
Explanation - The first dose of Hepatitis B vaccine is given within 24 hours of birth to prevent perinatal transmission.
Correct answer is: Hepatitis B
Q.2 The BCG vaccine provides protection primarily against which form of tuberculosis?
Pulmonary TB
Miliary TB
Latent TB
Reactivation TB
Explanation - BCG is more effective in preventing severe forms of TB such as miliary TB and tuberculous meningitis.
Correct answer is: Miliary TB
Q.3 Which of the following is a live attenuated vaccine?
Hepatitis B
MMR
Tetanus toxoid
Pneumococcal conjugate
Explanation - The MMR vaccine contains live attenuated viruses against measles, mumps, and rubella.
Correct answer is: MMR
Q.4 The DPT vaccine protects against which three diseases?
Diphtheria, Pertussis, Tetanus
Diphtheria, Polio, Typhoid
Diphtheria, Pertussis, Typhoid
Diphtheria, Polio, Tetanus
Explanation - DPT provides protection against diphtheria, pertussis (whooping cough), and tetanus.
Correct answer is: Diphtheria, Pertussis, Tetanus
Q.5 At what age is the first dose of MMR vaccine recommended in most national immunization schedules?
6 months
9 months
12 months
18 months
Explanation - In many countries, the first dose of MMR is recommended at 9 months of age.
Correct answer is: 9 months
Q.6 The oral polio vaccine (OPV) is an example of what type of vaccine?
Live attenuated
Inactivated
Toxoid
Subunit
Explanation - OPV contains live attenuated poliovirus strains.
Correct answer is: Live attenuated
Q.7 Which vaccine is administered as a nasal spray in some countries?
Influenza
Polio
MMR
Hepatitis B
Explanation - The live attenuated influenza vaccine can be given intranasally.
Correct answer is: Influenza
Q.8 Which of the following is a conjugate vaccine?
Polio
Hib
MMR
BCG
Explanation - Haemophilus influenzae type b (Hib) vaccine is a conjugate vaccine.
Correct answer is: Hib
Q.9 What is the route of administration of BCG vaccine?
Oral
Subcutaneous
Intradermal
Intramuscular
Explanation - BCG vaccine is given intradermally, usually on the upper arm.
Correct answer is: Intradermal
Q.10 Which of the following vaccines contains inactivated virus?
MMR
BCG
IPV
Yellow fever
Explanation - Inactivated polio vaccine (IPV) uses killed polioviruses.
Correct answer is: IPV
Q.11 The rotavirus vaccine is primarily given to prevent:
Respiratory infections
Severe diarrhea
Tuberculosis
Measles
Explanation - Rotavirus vaccine prevents severe diarrhea and dehydration in infants caused by rotavirus infection.
Correct answer is: Severe diarrhea
Q.12 The yellow fever vaccine is contraindicated in which group?
Pregnant women
Children above 9 months
Healthy adults
Travelers to endemic areas
Explanation - Yellow fever vaccine is a live vaccine and is contraindicated in pregnancy unless travel risk is very high.
Correct answer is: Pregnant women
Q.13 Which vaccine is associated with a scar formation at the injection site?
MMR
BCG
Polio
Hepatitis B
Explanation - BCG vaccine often leaves a scar on the upper arm due to the local immune response.
Correct answer is: BCG
Q.14 How many doses of HPV vaccine are recommended for adolescents aged 9-14 years?
1 dose
2 doses
3 doses
4 doses
Explanation - For adolescents 9–14 years, two doses of HPV vaccine are sufficient, while older individuals may need three doses.
Correct answer is: 2 doses
Q.15 Which vaccine is contraindicated in immunocompromised patients?
IPV
MMR
Hepatitis B
Tetanus toxoid
Explanation - Live attenuated vaccines like MMR should not be given to immunocompromised patients.
Correct answer is: MMR
Q.16 The pentavalent vaccine protects against how many diseases?
3
4
5
6
Explanation - Pentavalent vaccine protects against diphtheria, pertussis, tetanus, hepatitis B, and Hib.
Correct answer is: 5
Q.17 Which of the following vaccines is recommended for adolescents, particularly to prevent meningitis?
MMR
Meningococcal vaccine
Polio
Rotavirus
Explanation - The meningococcal vaccine is recommended to protect against meningitis, especially in adolescents and young adults.
Correct answer is: Meningococcal vaccine
Q.18 Which of the following vaccines is given at birth in most countries?
BCG
MMR
DPT
Hib
Explanation - BCG is given at birth to protect against severe forms of tuberculosis.
Correct answer is: BCG
Q.19 The chickenpox vaccine is an example of which type of vaccine?
Live attenuated
Inactivated
Toxoid
Subunit
Explanation - The varicella (chickenpox) vaccine is a live attenuated vaccine.
Correct answer is: Live attenuated
Q.20 Which of the following vaccines should not be given during pregnancy?
Tetanus toxoid
MMR
Influenza (inactivated)
Hepatitis B
Explanation - Live vaccines like MMR are contraindicated during pregnancy.
Correct answer is: MMR
Q.21 Which disease has been eradicated worldwide due to vaccination?
Smallpox
Polio
Measles
Diphtheria
Explanation - Smallpox was declared eradicated in 1980 due to widespread vaccination campaigns.
Correct answer is: Smallpox
Q.22 Which vaccine is recommended for travelers to areas with high incidence of hepatitis A?
Hepatitis A vaccine
Hepatitis B vaccine
Polio vaccine
MMR
Explanation - The hepatitis A vaccine is recommended for individuals traveling to endemic regions.
Correct answer is: Hepatitis A vaccine
Q.23 Which of the following vaccines is given orally?
OPV
Hepatitis B
DPT
MMR
Explanation - Oral polio vaccine is given orally as drops.
Correct answer is: OPV
Q.24 Which of the following vaccines is recommended for elderly adults to prevent pneumonia?
Pneumococcal vaccine
MMR
BCG
Rotavirus
Explanation - The pneumococcal vaccine is recommended for adults over 65 years and immunocompromised individuals.
Correct answer is: Pneumococcal vaccine
Q.25 Which vaccine provides protection against cervical cancer?
Hepatitis B
HPV
MMR
Varicella
Explanation - The HPV vaccine prevents infection with human papillomavirus strains that can cause cervical cancer.
Correct answer is: HPV