Q.1 Which of the following is the most common cause of acne vulgaris?
Staphylococcus aureus
Propionibacterium acnes
Herpes simplex virus
Candida albicans
Explanation - Acne vulgaris is primarily caused by Propionibacterium acnes, which proliferates in blocked sebaceous glands.
Correct answer is: Propionibacterium acnes
Q.2 A patient presents with silvery white scales on extensor surfaces. What is the most likely diagnosis?
Psoriasis
Eczema
Tinea corporis
Seborrheic dermatitis
Explanation - Psoriasis typically presents with silvery white scales over extensor surfaces like elbows and knees.
Correct answer is: Psoriasis
Q.3 Which vitamin deficiency is associated with dermatitis, diarrhea, and dementia?
Vitamin B1
Vitamin B3
Vitamin B6
Vitamin B12
Explanation - Niacin (Vitamin B3) deficiency causes pellagra, characterized by dermatitis, diarrhea, and dementia.
Correct answer is: Vitamin B3
Q.4 Which type of hypersensitivity reaction is responsible for urticaria?
Type I
Type II
Type III
Type IV
Explanation - Urticaria is caused by IgE-mediated mast cell degranulation, a Type I hypersensitivity reaction.
Correct answer is: Type I
Q.5 A 60-year-old man presents with tense blisters on his trunk. What is the most likely diagnosis?
Pemphigus vulgaris
Bullous pemphigoid
Dermatitis herpetiformis
Stevens-Johnson syndrome
Explanation - Bullous pemphigoid presents with tense, subepidermal blisters, common in elderly patients.
Correct answer is: Bullous pemphigoid
Q.6 Which skin condition is strongly associated with gluten sensitivity?
Eczema
Dermatitis herpetiformis
Psoriasis
Vitiligo
Explanation - Dermatitis herpetiformis is a chronic blistering skin condition linked with gluten sensitivity and celiac disease.
Correct answer is: Dermatitis herpetiformis
Q.7 The Auspitz sign is characteristic of which dermatologic disorder?
Lichen planus
Psoriasis
Seborrheic dermatitis
Erythema multiforme
Explanation - Auspitz sign, pinpoint bleeding after removal of scales, is a classic feature of psoriasis.
Correct answer is: Psoriasis
Q.8 Which condition is described as 'target lesions' on the skin?
Erythema nodosum
Erythema multiforme
Erythema marginatum
Erythema chronicum migrans
Explanation - Erythema multiforme is characterized by target-like lesions often following infections or drug use.
Correct answer is: Erythema multiforme
Q.9 What is the primary treatment for scabies?
Ketoconazole cream
Permethrin cream
Salicylic acid
Oral acyclovir
Explanation - Topical permethrin is the first-line treatment for scabies infestation.
Correct answer is: Permethrin cream
Q.10 A patient with hyperpigmented, velvety skin over axilla and neck is most likely suffering from?
Vitiligo
Acanthosis nigricans
Pityriasis versicolor
Lichen planus
Explanation - Acanthosis nigricans is associated with insulin resistance and appears as velvety hyperpigmentation.
Correct answer is: Acanthosis nigricans
Q.11 Koebner phenomenon is seen in which condition?
Vitiligo
Psoriasis
Atopic dermatitis
Tinea corporis
Explanation - Koebner phenomenon refers to the appearance of new lesions at the site of trauma, common in psoriasis.
Correct answer is: Psoriasis
Q.12 Which skin cancer is most associated with chronic sun exposure and has the best prognosis?
Melanoma
Basal cell carcinoma
Squamous cell carcinoma
Kaposi sarcoma
Explanation - Basal cell carcinoma is the most common skin cancer, slow growing, and rarely metastasizes.
Correct answer is: Basal cell carcinoma
Q.13 What is the first-line treatment for mild acne?
Topical corticosteroids
Topical retinoids
Oral antibiotics
Isotretinoin
Explanation - Topical retinoids are the mainstay of therapy for mild acne by reducing comedone formation.
Correct answer is: Topical retinoids
Q.14 Which of the following is a fungal infection of the skin?
Tinea corporis
Psoriasis
Lichen planus
Vitiligo
Explanation - Tinea corporis is a dermatophyte infection also known as ringworm.
Correct answer is: Tinea corporis
Q.15 A patient presents with hypopigmented patches that fluoresce under Wood’s lamp. The most likely diagnosis is?
Vitiligo
Tinea versicolor
Leprosy
Pityriasis alba
Explanation - Tinea versicolor caused by Malassezia species presents as hypopigmented patches with fluorescence.
Correct answer is: Tinea versicolor
Q.16 Which nail finding is most characteristic of psoriasis?
Beau’s lines
Onycholysis
Nail pitting
Koilonychia
Explanation - Nail pitting is a classic manifestation of psoriasis involving the nails.
Correct answer is: Nail pitting
Q.17 Stevens-Johnson syndrome is most commonly triggered by?
Bacterial infections
Drug reactions
Autoimmune disorders
Sun exposure
Explanation - SJS is a severe mucocutaneous reaction, usually triggered by medications such as sulfa drugs and anticonvulsants.
Correct answer is: Drug reactions
Q.18 Which autoimmune blistering disorder is characterized by intraepidermal blisters?
Pemphigus vulgaris
Bullous pemphigoid
Epidermolysis bullosa
Dermatitis herpetiformis
Explanation - Pemphigus vulgaris causes intraepidermal blisters due to autoantibodies against desmoglein.
Correct answer is: Pemphigus vulgaris
Q.19 Which condition presents with 'slapped cheek' rash in children?
Roseola
Fifth disease
Scarlet fever
Measles
Explanation - Fifth disease (erythema infectiosum) caused by parvovirus B19 is characterized by a slapped cheek rash.
Correct answer is: Fifth disease
Q.20 Vitiligo is caused by?
Fungal infection
Loss of melanocytes
Autoimmune hemolysis
Vitamin C deficiency
Explanation - Vitiligo results from autoimmune destruction of melanocytes, causing depigmented patches.
Correct answer is: Loss of melanocytes
Q.21 Which dermatologic disorder is associated with a 'herald patch' followed by a Christmas tree distribution?
Pityriasis rosea
Psoriasis
Lichen planus
Tinea corporis
Explanation - Pityriasis rosea often starts with a herald patch and progresses to a widespread rash in a Christmas tree pattern.
Correct answer is: Pityriasis rosea
Q.22 A patient presents with painful red nodules on the shins. The most likely diagnosis is?
Erythema nodosum
Erythema multiforme
Cellulitis
Dermatitis herpetiformis
Explanation - Erythema nodosum presents as tender, erythematous nodules over the shins, often associated with systemic diseases.
Correct answer is: Erythema nodosum
Q.23 Which bacterial infection causes honey-colored crusted lesions in children?
Cellulitis
Impetigo
Erysipelas
Furunculosis
Explanation - Impetigo, often caused by Staphylococcus aureus or Streptococcus pyogenes, produces honey-colored crusts.
Correct answer is: Impetigo
Q.24 What is the hallmark lesion of lichen planus?
Annular erythematous plaques
Purple polygonal pruritic papules
Silvery scaling plaques
Depigmented macules
Explanation - The hallmark of lichen planus is the 4 Ps: purple, polygonal, pruritic, papules.
Correct answer is: Purple polygonal pruritic papules
Q.25 Which dermatologic manifestation is common in systemic lupus erythematosus?
Butterfly rash
Target lesions
Slapped cheek rash
Herald patch
Explanation - SLE is commonly associated with a malar or butterfly rash across the cheeks and nose.
Correct answer is: Butterfly rash