Q.1 Which hormone is primarily responsible for male secondary sexual characteristics?
Estrogen
Testosterone
Progesterone
Cortisol
Explanation - Testosterone, produced mainly by the testes, is responsible for male secondary sexual characteristics such as facial hair, deepening of voice, and increased muscle mass.
Correct answer is: Testosterone
Q.2 Which of the following is the most common cause of erectile dysfunction in men over 50?
Psychological stress
Diabetes mellitus
Low testosterone
Excess exercise
Explanation - Diabetes mellitus can cause vascular and neuropathic damage, which are the most common causes of erectile dysfunction in older men.
Correct answer is: Diabetes mellitus
Q.3 What is the recommended screening method for prostate cancer in men over 50?
Digital rectal exam
Prostate-specific antigen (PSA) test
Transrectal ultrasound
MRI of pelvis
Explanation - PSA testing is commonly used to screen for prostate cancer, often combined with a digital rectal exam to improve detection.
Correct answer is: Prostate-specific antigen (PSA) test
Q.4 Which condition is characterized by a persistent, painful erection not related to sexual activity?
Erectile dysfunction
Priapism
Peyronie's disease
Hypogonadism
Explanation - Priapism is a prolonged, often painful erection that is unrelated to sexual stimulation and can lead to tissue damage if untreated.
Correct answer is: Priapism
Q.5 Which of the following is a major risk factor for developing benign prostatic hyperplasia (BPH)?
Obesity
Age
Smoking
Sedentary lifestyle
Explanation - BPH is strongly associated with aging, as the prostate enlarges naturally over time in men.
Correct answer is: Age
Q.6 Which vitamin deficiency is associated with reduced testosterone levels?
Vitamin A
Vitamin D
Vitamin C
Vitamin B12
Explanation - Vitamin D deficiency has been linked to lower testosterone levels, potentially affecting male reproductive health.
Correct answer is: Vitamin D
Q.7 Which sexually transmitted infection can lead to epididymitis in men?
Chlamydia
HIV
Hepatitis B
Influenza virus
Explanation - Chlamydia is a common cause of epididymitis in sexually active men, presenting with scrotal pain and swelling.
Correct answer is: Chlamydia
Q.8 Low sperm count is medically termed as:
Azoospermia
Oligospermia
Oliguria
Polyuria
Explanation - Oligospermia refers to a lower than normal sperm count, which can contribute to male infertility.
Correct answer is: Oligospermia
Q.9 Which lifestyle change is most effective in improving erectile dysfunction in men with obesity?
Increased alcohol intake
Regular exercise and weight loss
High-protein diet
Smoking cessation alone
Explanation - Exercise and weight reduction improve cardiovascular health, which directly improves erectile function in men with obesity.
Correct answer is: Regular exercise and weight loss
Q.10 Which of the following medications can cause erectile dysfunction as a side effect?
Beta-blockers
Paracetamol
Antacids
Vitamin E
Explanation - Certain medications, such as beta-blockers and some antidepressants, can contribute to erectile dysfunction.
Correct answer is: Beta-blockers
Q.11 Which condition involves the curvature of the penis due to fibrous plaque formation?
Priapism
Peyronie's disease
Hydrocele
Varicocele
Explanation - Peyronie's disease is caused by fibrous plaque in the tunica albuginea, leading to painful penile curvature.
Correct answer is: Peyronie's disease
Q.12 Which hormone level is typically low in men with hypogonadism?
Testosterone
Cortisol
Thyroxine
Insulin
Explanation - Hypogonadism is characterized by low testosterone production, leading to symptoms such as decreased libido, fatigue, and reduced muscle mass.
Correct answer is: Testosterone
Q.13 Which type of prostate cancer screening is controversial due to risk of overdiagnosis?
PSA screening
Digital rectal exam
MRI
CT scan
Explanation - Routine PSA screening can detect slow-growing prostate cancers that may never cause symptoms, leading to potential overdiagnosis and overtreatment.
Correct answer is: PSA screening
Q.14 Which is a common cause of infertility in men related to varicocele?
Increased testicular temperature
Low testosterone production
Blocked urethra
Frequent infections
Explanation - Varicocele can increase the temperature of the testes, impairing sperm production and quality, leading to infertility.
Correct answer is: Increased testicular temperature
Q.15 Which of the following is the most common type of testicular cancer?
Seminoma
Leydig cell tumor
Sertoli cell tumor
Lymphoma
Explanation - Seminoma is the most common type of testicular cancer in men aged 30–40 and has a good prognosis with early treatment.
Correct answer is: Seminoma
Q.16 Which of the following is a preventable cause of male infertility?
Genetic mutations
Varicocele
Klinefelter syndrome
Cryptorchidism
Explanation - Varicocele is a treatable and potentially preventable cause of male infertility, often corrected surgically.
Correct answer is: Varicocele
Q.17 Which lifestyle factor is strongly associated with decreased testosterone levels in men?
Smoking
Excessive alcohol consumption
High fiber diet
Regular exercise
Explanation - Chronic alcohol consumption can impair testosterone synthesis and disrupt the hypothalamic-pituitary-gonadal axis.
Correct answer is: Excessive alcohol consumption
Q.18 Which viral infection is most strongly associated with male infertility?
Mumps
Influenza
Hepatitis A
Varicella
Explanation - Mumps orchitis can cause testicular inflammation and damage, leading to reduced fertility in men.
Correct answer is: Mumps
Q.19 Which of the following is the first-line treatment for mild erectile dysfunction?
Testosterone therapy
Phosphodiesterase-5 inhibitors
Penile implant
Psychotherapy only
Explanation - Medications like sildenafil are first-line therapy for mild to moderate erectile dysfunction, often combined with lifestyle modification.
Correct answer is: Phosphodiesterase-5 inhibitors
Q.20 Which is the most common symptom of BPH?
Hematuria
Difficulty urinating
Testicular pain
Erectile dysfunction
Explanation - BPH commonly causes urinary symptoms such as difficulty starting urination, weak stream, and frequent urination.
Correct answer is: Difficulty urinating
Q.21 Which condition is characterized by the inability to achieve or maintain an erection sufficient for sexual intercourse?
Premature ejaculation
Erectile dysfunction
Peyronie's disease
Priapism
Explanation - Erectile dysfunction is the persistent inability to achieve or maintain an erection sufficient for satisfactory sexual performance.
Correct answer is: Erectile dysfunction
Q.22 Which male reproductive organ is primarily responsible for sperm production?
Prostate
Epididymis
Testes
Seminal vesicles
Explanation - The testes produce sperm in the seminiferous tubules and secrete testosterone.
Correct answer is: Testes
Q.23 Which type of testosterone therapy is preferred for men with hypogonadism who want to maintain fertility?
Injectable testosterone
Transdermal patches
Clomiphene citrate
Oral testosterone undecanoate
Explanation - Clomiphene stimulates endogenous testosterone production without suppressing spermatogenesis, preserving fertility.
Correct answer is: Clomiphene citrate
Q.24 Which screening test is recommended for men with a family history of testicular cancer?
Routine ultrasound
Monthly testicular self-exam
PSA test
MRI of testes
Explanation - Testicular self-exam helps in early detection of testicular cancer, especially in high-risk men with family history.
Correct answer is: Monthly testicular self-exam
Q.25 Which of the following can be a side effect of androgen abuse in men?
Gynecomastia
Hair loss
Mood swings
All of the above
Explanation - Androgen or anabolic steroid abuse can lead to gynecomastia, male-pattern baldness, mood changes, and cardiovascular risks.
Correct answer is: All of the above