Q.1 Which virus is primarily responsible for causing chickenpox?
Herpes simplex virus
Varicella-zoster virus
Human papillomavirus
Molluscum contagiosum virus
Explanation - Chickenpox is caused by the varicella-zoster virus, a member of the herpesvirus family.
Correct answer is: Varicella-zoster virus
Q.2 Which viral infection is characterized by small, flesh-colored, umbilicated papules?
Molluscum contagiosum
Herpes zoster
Measles
Warts
Explanation - Molluscum contagiosum presents as small, dome-shaped, flesh-colored papules with a central depression (umbilication).
Correct answer is: Molluscum contagiosum
Q.3 Which virus causes genital warts?
Human papillomavirus
Varicella-zoster virus
Herpes simplex virus type 2
Coxsackievirus
Explanation - Genital warts are caused by human papillomavirus (HPV), especially types 6 and 11.
Correct answer is: Human papillomavirus
Q.4 Which complication is most commonly associated with herpes zoster?
Postherpetic neuralgia
Scarring
Secondary bacterial infection
Hyperpigmentation
Explanation - Herpes zoster can cause severe pain that persists after the rash heals, known as postherpetic neuralgia.
Correct answer is: Postherpetic neuralgia
Q.5 Hand, foot, and mouth disease is caused by which virus?
Coxsackievirus A16
Varicella-zoster virus
Epstein-Barr virus
Measles virus
Explanation - Hand, foot, and mouth disease is commonly caused by Coxsackievirus A16, producing vesicles on hands, feet, and oral mucosa.
Correct answer is: Coxsackievirus A16
Q.6 Which viral skin infection presents with grouped vesicles on an erythematous base?
Herpes simplex
Molluscum contagiosum
Warts
Measles
Explanation - Herpes simplex virus infections typically present with clusters of small vesicles on a red base.
Correct answer is: Herpes simplex
Q.7 Which viral infection is preventable by the MMR vaccine?
Measles
Molluscum contagiosum
Herpes zoster
Warts
Explanation - The MMR vaccine protects against measles, mumps, and rubella.
Correct answer is: Measles
Q.8 Which virus remains latent in dorsal root ganglia and can reactivate later in life?
Varicella-zoster virus
Human papillomavirus
Measles virus
Coxsackievirus
Explanation - Varicella-zoster virus can remain dormant in sensory ganglia and reactivate as shingles.
Correct answer is: Varicella-zoster virus
Q.9 Which viral infection of the skin is characterized by Koebner phenomenon?
Warts
Molluscum contagiosum
Measles
Herpes simplex
Explanation - Human papillomavirus-induced warts may appear at sites of trauma, known as the Koebner phenomenon.
Correct answer is: Warts
Q.10 Which virus is associated with Kaposi's sarcoma in immunocompromised patients?
Human herpesvirus 8
Herpes simplex virus 1
Varicella-zoster virus
Coxsackievirus
Explanation - Kaposi's sarcoma is linked to infection with HHV-8, especially in patients with HIV/AIDS.
Correct answer is: Human herpesvirus 8
Q.11 Which viral exanthem starts on the face and spreads to the trunk and limbs?
Measles
Chickenpox
Rubella
Roseola
Explanation - Measles rash typically begins on the face and spreads downwards to the trunk and extremities.
Correct answer is: Measles
Q.12 Which viral skin infection presents with dew-drop on a rose petal appearance?
Chickenpox
Measles
Molluscum contagiosum
Warts
Explanation - Chickenpox lesions often appear as vesicles on an erythematous base, described as dew-drop on a rose petal.
Correct answer is: Chickenpox
Q.13 Which virus causes herpangina in children?
Coxsackievirus
Varicella-zoster virus
Measles virus
Rubella virus
Explanation - Coxsackievirus infections can cause herpangina, characterized by vesicles on the soft palate and uvula.
Correct answer is: Coxsackievirus
Q.14 Which of the following is the most common site for herpes zoster rash?
Thoracic dermatomes
Face
Hands
Feet
Explanation - Herpes zoster commonly affects thoracic dermatomes, causing a unilateral, dermatomal rash.
Correct answer is: Thoracic dermatomes
Q.15 Which viral skin infection is associated with erythema infectiosum (slapped cheek syndrome)?
Parvovirus B19
Measles virus
Varicella-zoster virus
Coxsackievirus
Explanation - Erythema infectiosum is caused by parvovirus B19, presenting with a bright red rash on the cheeks.
Correct answer is: Parvovirus B19
Q.16 Which virus is primarily responsible for common warts on hands and fingers?
Human papillomavirus
Herpes simplex virus
Varicella-zoster virus
Coxsackievirus
Explanation - Common warts are caused by HPV, especially types 1, 2, and 4.
Correct answer is: Human papillomavirus
Q.17 Which viral infection can cause congenital abnormalities if contracted during pregnancy?
Rubella
Chickenpox
Herpes simplex
Molluscum contagiosum
Explanation - Maternal rubella infection can lead to congenital rubella syndrome in the fetus.
Correct answer is: Rubella
Q.18 Which virus is responsible for orf infection, a zoonotic skin infection?
Parapoxvirus
Human papillomavirus
Coxsackievirus
Varicella-zoster virus
Explanation - Orf is a zoonotic infection caused by parapoxvirus, transmitted from sheep and goats to humans.
Correct answer is: Parapoxvirus
Q.19 Which viral infection is characterized by rapid onset of fever followed by a maculopapular rash that fades in 2–3 days?
Roseola
Measles
Rubella
Chickenpox
Explanation - Roseola, caused by HHV-6, presents with high fever that resolves abruptly, followed by a short-lived rash.
Correct answer is: Roseola
Q.20 Which virus can cause verrucae planae (flat warts) on the face?
Human papillomavirus
Varicella-zoster virus
Herpes simplex virus
Coxsackievirus
Explanation - Verrucae planae are flat-topped warts caused by HPV, often seen on the face and hands.
Correct answer is: Human papillomavirus
Q.21 Which viral infection is highly contagious and spreads via respiratory droplets before rash appears?
Measles
Molluscum contagiosum
Warts
Herpes simplex
Explanation - Measles is highly contagious and transmissible during the prodromal phase via respiratory droplets.
Correct answer is: Measles
Q.22 Which viral skin infection can lead to secondary bacterial infections if lesions are scratched?
Chickenpox
Warts
Molluscum contagiosum
Roseola
Explanation - Scratching chickenpox lesions can introduce bacteria, causing secondary infections.
Correct answer is: Chickenpox
Q.23 Which virus causes cold sores primarily around the mouth?
Herpes simplex virus type 1
Herpes simplex virus type 2
Varicella-zoster virus
Coxsackievirus
Explanation - HSV-1 commonly causes recurrent cold sores or fever blisters around the oral region.
Correct answer is: Herpes simplex virus type 1
Q.24 Which viral skin infection often resolves spontaneously in children without specific treatment?
Molluscum contagiosum
Herpes zoster
Measles
Chickenpox
Explanation - Molluscum contagiosum in children is self-limiting and often resolves without therapy within months.
Correct answer is: Molluscum contagiosum
Q.25 Which viral infection causes lesions that follow a dermatomal pattern?
Herpes zoster
Measles
Molluscum contagiosum
Warts
Explanation - Herpes zoster reactivation produces vesicular lesions along the distribution of a single sensory dermatome.
Correct answer is: Herpes zoster